General
Preferred name
Indolmycin
Synonyms
INDOMYCIN ()
P&D ID
PD018686
CAS
21200-24-8
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Indolmycin competitively inhibits bacterial tryptophanyl-tRNA synthetases. It has antibacterial activity against MSSA (methicillin-susceptible Staphylococcus aureus), MRSA (methicillin-resistant S. aureus) and VISA (vancomycin-intermediate S. aureus) . The compound also has antimalarial activity .

The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY. (GtoPdb)
Compound Sets
3
Cayman Chemical Bioactives
15385
Guide to Pharmacology
11021
Novartis Chemogenetic Library (NIBR MoA Box)
External IDs
24
Properties
(calculated by RDKit )
Molecular Weight
257.12
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
2
cLogP
1.77
TPSA
66.48
Fraction CSP3
0.29
Chiral centers
2.0
Largest ring
6.0
QED
0.86
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Member status
member
Source data