General
Preferred name
Prefolic A
Synonyms
NSC173328 ()
Calcium N5-methyltetrahydrofolate ()
5-Methyltetrahydrofolic Acid ()
5-Methyl THF ()
5-Methyl THF (calcium) ()
5-Methyltetrahydrofolic Acid (hydrate) ()
P&D ID
PD018431
CAS
26560-38-3
134-35-0
Tags
drug candidate
natural product
available
Drug Status
nutraceutical
investigational
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
5
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
36
Properties
(calculated by RDKit )
Molecular Weight
459.19
Hydrogen Bond Acceptors
9
Hydrogen Bond Donors
7
Rotatable Bonds
9
Ring Count
3
Aromatic Ring Count
2
cLogP
-0.26
TPSA
202.77
Fraction CSP3
0.35
Chiral centers
2.0
Largest ring
6.0
QED
0.26
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolic Enzyme/Protease
Cell Cycle/DNA Damage
Target
Endogenous Metabolite
Antifolate
Source data
