General
Preferred name
CANNABIGEROL
Synonyms
Cannabigerol-d9 ()
Cannabigerol (CRM) ()
Cannabigerol-d9 (CRM) ()
Cannabigerol (Alt. Batch CRM) ()
P&D ID
PD018275
CAS
25654-31-3
Tags
drug candidate
natural product
available
Drug Status
experimental
investigational
Max Phase
2.0
Drug indication
Anxiety
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Cannabigerol (CBG) is a phytocannabinoid that is a biosynthetic presursor for the synthesis of other cannabinoids. It is a minor constituent of herbal cannabis.
(GtoPdb)
PRICE
375
DESCRIPTION
Cannabigerol is a high affinity ????2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also binds to the CB2 receptor; it can relieve interocular pressure, which may be of benefit in the treatment of glaucoma.
DESCRIPTION
Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also binds to the CB2 receptor; it can relieve interocular pressure, which may be of benefit in the treatment of glaucoma.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
0
Compound Sets
5
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
27
Molecular Weight
316.24
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
9
Ring Count
1
Aromatic Ring Count
1
cLogP
6.07
TPSA
40.46
Fraction CSP3
0.52
Chiral centers
0.0
Largest ring
6.0
QED
0.43
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
5-HT
NOS
ROS
Pathway
GPCR/G protein
Immunology/Inflammation
Neuroscience
Source data
