General
Preferred name
(±)11(12)-EET
Synonyms
11S(12R)-EET ()
P&D ID
PD018242
CAS
123931-40-8
87173-81-7
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
11, 12-Epoxyeicosatrienoic acid is an epoxyeicosatrienoic acid (EET). Induction of CYP2C8 in native coronary artery endothelial cells by beta-naphthoflavone enhances the formation of 11, 12-epoxyeicosatrienoic acid, as well as endothelium-derived hyperpolarizing factor-mediated hyperpolarization and relaxatioocoagulation. It also has anti-inflammatory, angiogenic, and cardioprotective properties.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
3
BOC Sciences Bioactive Compounds
Other bioactive compounds
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[[ ligand_id ]]
free of charge
External IDs
18
Molecular Weight
320.24
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
14
Ring Count
1
Aromatic Ring Count
0
cLogP
5.43
TPSA
49.83
Fraction CSP3
0.65
Chiral centers
2.0
Largest ring
3.0
QED
0.26
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
