General
Preferred name
FIALURIDINE
Synonyms
DRG-0098 ()
FIAU ()
NSC 678514 ()
Fialuridina ()
NSC-678514 ()
P&D ID
PD018188
CAS
69123-98-4
Tags
available
drug candidate
Drug indication
Hepatitis B virus infection
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
92
DESCRIPTION
Fialuridine (DRG-0098) is a DNA-directed DNA polymerase inhibitor potentially for the treatment of HBV infection with potent activity against hepatitis B virus in vitro and in vivo.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
7
Cayman Chemical Bioactives
ChEMBL Drugs
DrugBank
DrugMAP
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
22
Molecular Weight
371.96
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
3
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
1
cLogP
-1.27
TPSA
104.55
Fraction CSP3
0.56
Chiral centers
4.0
Largest ring
6.0
QED
0.56
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
DNA polymerase
CMV
Pathway
Cell Cycle/Checkpoint
DNA Damage/DNA Repair
Source data
