General
Preferred name
coenzyme A
Synonyms
CoASH ()
COENZYME_A ()
Coenzyme A (sodium salt) ()
Coenzyme A (lithium salt hydrate) ()
Coenzyme A (free acid) ()
P&D ID
PD018044
CAS
85-61-0
55672-92-9
Tags
available
drug candidate
Drug indication
Discovery agent
Hyperlipoproteinemia
Drug Status
nutraceutical
investigational
Max Phase
3.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
57
DESCRIPTION
Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
14
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Concise Guide to Pharmacology 2025/26
Drug Repurposing Hub
DrugBank
DrugMAP
Guide to Pharmacology
Other bioactive compounds
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
66
Molecular Weight
767.12
Hydrogen Bond Acceptors
18
Hydrogen Bond Donors
10
Rotatable Bonds
18
Ring Count
3
Aromatic Ring Count
2
cLogP
-1.67
TPSA
346.56
Fraction CSP3
0.67
Chiral centers
7.0
Largest ring
6.0
QED
0.06
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
Human Endogenous Metabolite
ACAT2, CRAT, CS, DBI, HMGCR, KAT2A, KAT2B, KAT5
Pathway
Metabolism
Source data
