General
Preferred name
(Z)-PUGNAc
Synonyms
PUGNAC ()
P&D ID
PD017856
CAS
132489-69-1
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION (Z)-PUGNAc is a potent O-GlcNAcase inhibitor. (Z)-PUGNAc is a vastly more potent inhibitor of O-GlcNAcase than the E form[1].
Compound Sets
3
Cayman Chemical Bioactives
17151
MedChem Express Bioactive Compound Library
HY-108241
Novartis Chemogenetic Library (NIBR MoA Box)
External IDs
24
Properties
(calculated by RDKit )
Molecular Weight
353.12
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
5
Rotatable Bonds
4
Ring Count
2
Aromatic Ring Count
1
cLogP
-0.83
TPSA
149.71
Fraction CSP3
0.4
Chiral centers
4.0
Largest ring
6.0
QED
0.35
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Member status
virtual
MOA
Hexosaminidase A inhibitor
Pathway
Neuronal Signaling
Target
OGA
Source data