General
Preferred name
THIODIGALACTOSIDE
Synonyms
TDG ()
P&D ID
PD017601
CAS
80441-61-8
51555-87-4
Tags
available
drug candidate
Drug Status
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
DESCRIPTION Thiodigalactoside (TDG), a non-metabolizable disaccharide, serves as an orally active, potent galectin (GAL) inhibitor, exhibiting Kd values of 24 ??M and 49 ??M for GAL1 and GAL3, respectively. Demonstrating anti-inflammatory and anti-cancer properties, it significantly diminishes body weight gain in diet-induced obese rats.
DESCRIPTION Thiodigalactoside (TDG), a non-metabolizable disaccharide, serves as an orally active, potent galectin (GAL) inhibitor, exhibiting Kd values of 24 μM and 49 μM for GAL1 and GAL3, respectively. Demonstrating anti-inflammatory and anti-cancer properties, it significantly diminishes body weight gain in diet-induced obese rats. (TargetMol Bioactive Compound Library)
Compound Sets
4
Cayman Chemical Bioactives
17154
DrugBank
DB04396
MedChem Express Bioactive Compound Library
HY-130208
TargetMol Bioactive Compound Library
T38074
External IDs
19
Properties
(calculated by RDKit )
Molecular Weight
358.09
Hydrogen Bond Acceptors
11
Hydrogen Bond Donors
8
Rotatable Bonds
4
Ring Count
2
Aromatic Ring Count
0
cLogP
-4.68
TPSA
180.3
Fraction CSP3
1.0
Chiral centers
10.0
Largest ring
6.0
QED
0.24
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Galectin
Pathway
Immunology/Inflammation
Source data