General
Preferred name
Uniconazole
Synonyms
XE 1019D ()
Uniconazole (S 3307D) ()
P&D ID
PD017589
CAS
76714-83-5
83657-22-1
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Uniconazole, a plant growth retardant, is a potent inhibitor of abscisic acid (ABA) catabolism with an IC50 of 68 nM against ABA 8¡¯-hydroxylase. Uniconazole is a potent competitive inhibitor of CYP707A3 activity with a Ki of 8 nM. Uniconazole evidently inhibits gibberellin biosynthesis, and brassinosteroid biosynthesis is also inhibited to some extent[1].
PRICE 29
DESCRIPTION Uniconazole is a plant growth regulator that inhibit cytochrome P450 707As (Ki=68 nM). CYP707As is a major ABA catabolic enzyme that catabolize Abscisic acid, accordingly suppress gibberellin and sterol biosynthesis. (TargetMol Bioactive Compound Library)
Compound Sets
4
Cayman Chemical Bioactives
17852
MedChem Express Bioactive Compound Library
HY-B0873
Selleckchem Bioactive Compound Library
uniconazole
TargetMol Bioactive Compound Library
T21482
External IDs
20
Properties
(calculated by RDKit )
Molecular Weight
291.11
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
2
cLogP
3.34
TPSA
50.94
Fraction CSP3
0.33
Chiral centers
1.0
Largest ring
6.0
QED
0.94
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
707As
Cytochrome P450
ROS Kinase
P450 (e.g. CYP17)
Pathway
Metabolic Enzyme/Protease
Protein Tyrosine Kinase/RTK
Metabolism
Tyrosine Kinase/Adaptors
Source data