General
Preferred name
LACTISOLE SODIUM
Synonyms
Lactisole ()
P&D ID
PD017400
CAS
150767-88-7
150436-68-3
Tags
drug candidate
natural product
available
Drug Status
investigational
Max Phase
Phase 1
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Lactisole is a sweet taste receptor antagonist that suppresses perception of sweetness in humans. It blocks a heterodimeric receptor comprised of T1R2+T1R3, which detects sweet-tasting compounds. (BOC Sciences Bioactive Compounds)
Compound Sets
4
BOC Sciences Bioactive Compounds
2-p-methoxyphenoxy-propionic-acid-cas-150436-68-3-item-199888
Cayman Chemical Bioactives
18657
ChEMBL Drugs
CHEMBL3715108
MedChem Express Bioactive Compound Library
HY-W030796A
External IDs
13
Properties
(calculated by RDKit )
Molecular Weight
218.06
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
4
Ring Count
1
Aromatic Ring Count
1
cLogP
-2.78
TPSA
58.59
Fraction CSP3
0.3
Chiral centers
1.0
Largest ring
6.0
QED
0.51
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Target
Taste receptor
Source data