General
Preferred name
Adenosine disphosphate
Synonyms
ADENOSINE DIPHOSPHATE ()
adenosine pyrophosphate ()
ADP ()
Adenosine 5'-diphosphate ()
Adenosine diphosphate, adenosine pyrophosphate, Adenosine 5'-diphosphate ()
Adenosine-5'-diphosphate ()
Adenosine 5'-diphosphate (potassium salt) ()
Adenosine 5'-diphosphate sodium salt ()
P&D ID
PD017263
CAS
18389-49-6
58-64-0
70285-70-0
20398-34-9
Tags
available
drug candidate
Drug Status
investigational
Max Phase
0.5
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
PRICE
29
DESCRIPTION
Adenosine 5'-diphosphate sodium salt (ADP sodium salt) is an adenine nucleotide that is phosphorylated into ATP by ATPase. This phosphorylation is a key part of cellular homeostatis as it allows for energy storage and is involved in nucleic acid metabolism. ADP affects platelet activation through its interaction with ADP receptors P2Y1, P2Y12 and P2X1. Upon its conversion to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.
DESCRIPTION
ADP is an ATP hydrolysis product and an agonist of a P2Y purinoceptor 13 with IC50 = 0.07 nM
(Enamine Bioactive Compounds)
DESCRIPTION
Adenosine 5'-diphosphate (ADP) is a naturally occurring nucleotide derived from the dephosphorylation of ATP. Adenosine 5'-diphosphate is essential for cellular metabolism and induces platelet aggregation.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
0
Compound Sets
18
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
CZ-OPENSCREEN Bioactive Library
DrugBank
DrugMAP
Enamine Bioactive Compounds
EU-OPENSCREEN Bioactive Compound Library
EUbOPEN Chemogenomics Library
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
Other bioactive compounds
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
84
Molecular Weight
427.03
Hydrogen Bond Acceptors
12
Hydrogen Bond Donors
6
Rotatable Bonds
6
Ring Count
3
Aromatic Ring Count
2
cLogP
-1.75
TPSA
232.6
Fraction CSP3
0.5
Chiral centers
5.0
Largest ring
6.0
QED
0.28
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
Pathway
Metabolism
Metabolic Enzyme/Protease
Recommended Cell Concentration
None
Source data
