General
Preferred name
LICARBAZEPINE
Synonyms
10,11-hydroxy-10,11 Dihydrocarbamezer ()
BIA 2-005 ()
GP 47779 ()
10,11-dihydro-10-hydroxy Carbamazepine ()
10-hydroxy-carbamazepine ()
Licarbazepina ()
P&D ID
PD017222
CAS
29331-92-8
Tags
available
drug candidate
Drug indication
Bipolar disorder
Epilepsy
Drug Status
investigational
Max Phase
3.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Licarbazepine (BIA 2-005; GP 47779) is a voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects[1].
PRICE
36
DESCRIPTION
Active metabolite of oxcarbazepine (Cat. No. 3864)
(Tocriscreen Plus)
DESCRIPTION
Active metabolite of oxcarbazepine (Cat. No. 3684)
(Tocriscreen Total)
DESCRIPTION
Licarbazepine (10,11-hydroxy-10,11 Dihydrocarbamezer) is the pharmacologically active metabolite of oxcarbazepine, a drug indicated for the treatment of partial seizures and bipolar disorders.
(TargetMol Bioactive Compound Library)
DESCRIPTION
TRPV1 antagonist
(Tocris Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
10
Cayman Chemical Bioactives
ChEMBL Drugs
DrugMAP
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
ReFrame library
TargetMol Bioactive Compound Library
Tocris Bioactive Compound Library
Tocriscreen Plus
Tocriscreen Total
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
25
Molecular Weight
254.11
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
0
Ring Count
3
Aromatic Ring Count
2
cLogP
2.49
TPSA
66.56
Fraction CSP3
0.13
Chiral centers
1.0
Largest ring
7.0
QED
0.76
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
Ion Channels
Primary Target
Voltage-gated Sodium (NaV) Channels
MOA
Blocker
Pathway
Membrane Transporter/Ion Channel
Target
Sodium Channel
Source data
