General
Preferred name
SCH 442416
Synonyms
SCH442416 ()
SCH-442416 ()
P&D ID
PD016930
CAS
316173-57-6
Tags
available
drug candidate
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Potent, selective A1 agonist (Tocris Bioactive Compound Library)
Cell lines
0
Organisms
1
Compound Sets
12
Axon Medchem Screening Library
1264
Cayman Chemical Bioactives
22233
Concise Guide to Pharmacology 2017/18
3283
Concise Guide to Pharmacology 2019/20
3283
Concise Guide to Pharmacology 2021/22
3283
Concise Guide to Pharmacology 2023/24
3283
DrugMAP
DMQ2K1V
Guide to Pharmacology
3283
MedChem Express Bioactive Compound Library
HY-103169
Selleckchem Bioactive Compound Library
sch-442416
TargetMol Bioactive Compound Library
T23336
Tocris Bioactive Compound Library
2463
External IDs
21
Properties
(calculated by RDKit )
Molecular Weight
389.16
Hydrogen Bond Acceptors
9
Hydrogen Bond Donors
1
Rotatable Bonds
6
Ring Count
5
Aromatic Ring Count
5
cLogP
2.96
TPSA
109.29
Fraction CSP3
0.2
Chiral centers
0.0
Largest ring
6.0
QED
0.48
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Target
A2A
A2A antagonist
Adenosine Receptor
Primary Target
Adenosine A2A Receptors
MOA
Antagonist
Source data