General
Preferred name
TENILSETAM
Synonyms
Piperazinone ()
P&D ID
PD016815
CAS
85606-97-9
86696-86-8
Tags
available
drug candidate
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
144
DESCRIPTION
Tenilsetam is an endonuclease modulator, also a nootropic agent and advanced glycation end product (AGE) inhibitor with the potential to treat Alzheimer's disease (AD). Preclinical studies indicated that tenilsetam may have an inhibitory effect on diabetic retinopathy, without amelioration of pericyte loss.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Tenilsetam (Piperazinone) is an endonuclease modulator; a nootropic agent and advanced glycation end product (AGE) inhibitor having potential for Alzheimer's disease (AD) treatment.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
7
Axon Medchem Screening Library
BOC Sciences Bioactive Compounds
ChEMBL Drugs
DrugMatrix
Enamine BioReference Compounds
ReFrame library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
16
Molecular Weight
182.05
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
1
Ring Count
2
Aromatic Ring Count
1
cLogP
0.51
TPSA
41.13
Fraction CSP3
0.38
Chiral centers
1.0
Largest ring
6.0
QED
0.66
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
AGE
AGE inhibitor
Source data
