General
Preferred name
CNQX
Synonyms
FG9065 ()
[3H]CNQX ()
CNQX (disodium) ()
FG9065 (disodium) ()
6-cyano-7-nitroquinoxaline-2,3-dione ()
P&D ID
PD016792
CAS
115066-14-3
479347-85-8
Tags
available
drug candidate
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Non-selective endogenous glycine receptor agonist (Tocris Bioactive Compound Library)
DESCRIPTION Potent AMPA/kainate antagonist (Tocriscreen Total)
Compound Sets
19
AdooQ Bioactive Compound Library
A16109
Axon Medchem Screening Library
1200
Cayman Chemical Bioactives
14618
Concise Guide to Pharmacology 2017/18
4081
Concise Guide to Pharmacology 2019/20
4081
Concise Guide to Pharmacology 2021/22
4081
Concise Guide to Pharmacology 2023/24
4081
Drug Repurposing Hub
DrugMAP
DMIFKUX
DrugMatrix
EU-OPENSCREEN Bioactive Compound Library
EOS101186
Guide to Pharmacology
4081
5475
Ki Database
CNQX
MedChem Express Bioactive Compound Library
HY-15066
HY-15066A
ReFrame library
Selleckchem Bioactive Compound Library
cnqx
TargetMol Bioactive Compound Library
T7178
Tocris Bioactive Compound Library
0190
Tocriscreen Total
External IDs
27
Properties
(calculated by RDKit )
Molecular Weight
232.02
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
1
Ring Count
2
Aromatic Ring Count
2
cLogP
0.0
TPSA
132.65
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.41
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Neuroscience
Membrane Transporter/Ion Channel
Neuronal Signaling
Target
AMPA
GRIA1, GRIA2, GRIA3, GRIA4
AMPA/Kainate antagonist
iGluR
GluR
Primary Target
AMPA Receptors
MOA
Antagonist
glutamate receptor antagonist
Source data