General
Preferred name
EBPC
Synonyms
P&D ID
PD016789
CAS
4450-98-0
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
108
DESCRIPTION
EBPC is a potent, selective inhibitor of aldose reductase. EBPC has been used to improve the cytotoxic effects of the anticancer agents doxorubicin and cisplatin in HeLa cervical carcinoma cells.
(Enamine Bioactive Compounds)
DESCRIPTION
EBPC is a potent and selective aldose reductase inhibitor. It is used to improve the cytotoxicity of anticancer reagents such as cisplatin and doxorubicin in HeLa cervical carcinoma cells via an increase in ERK activity.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Aldose reductase inhibitor
(Tocriscreen Total)
DESCRIPTION
EBPC is an inhibitor of aldose reductase.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
9
Axon Medchem Screening Library
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
DrugMatrix
Enamine Bioactive Compounds
Enamine BioReference Compounds
TargetMol Bioactive Compound Library
Tocriscreen Total
ZINC Tool Compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
20
Molecular Weight
261.1
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
2
Aromatic Ring Count
1
cLogP
1.4
TPSA
66.84
Fraction CSP3
0.29
Chiral centers
0.0
Largest ring
6.0
QED
0.83
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Aldose Reductase
Aldose reductase inhibitor
Pathway
Endocrinology/Hormones
Metabolism
Source data
