General
Preferred name
ASOPRISNIL
Synonyms
J867 ()
J-867 ()
BAY86-5294 ()
P&D ID
PD016637
CAS
199396-76-4
Tags
available
drug candidate
natural product
Drug indication
Endometriosis
Drug Status
investigational
Max Phase
Phase 3
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Asoprisnil is a selective progesterone receptor (PR) modulator developed for the treatment of progesterone sensitive myomata.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
10
Axon Medchem Screening Library
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Drugs
DrugBank
DrugMAP
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
21
Molecular Weight
449.26
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
1
Rotatable Bonds
5
Ring Count
5
Aromatic Ring Count
1
cLogP
5.43
TPSA
68.12
Fraction CSP3
0.57
Chiral centers
5.0
Largest ring
6.0
QED
0.37
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
PR modulator
Progesterone Receptor
Pathway
Vitamin D Related/Nuclear Receptor
Source data
