General
Preferred name
Infigratinib phosphate
Synonyms
NVP-BGJ398 phosphate ()
BGJ-398 phosphate ()
NVP-BGJ398 (phosphate) ()
Infigratinib monophosphate ()
Truseltiq ()
P&D ID
PD016507
CAS
872511-34-7
1310746-10-1
Tags
available
drug
Drug Status
approved
Max Phase
Phase 4
First approval
2021
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
5
Organisms
0
Compound Sets
6
Axon Medchem Screening Library
ChEMBL Approved Drugs
ChEMBL Drugs
LSP-MoA library (Laboratory of Systems Pharmacology)
LSP-OptimalKinase library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
10
Properties
(calculated by RDKit )
Molecular Weight
657.16
Hydrogen Bond Acceptors
9
Hydrogen Bond Donors
5
Rotatable Bonds
8
Ring Count
4
Aromatic Ring Count
3
cLogP
4.43
TPSA
172.85
Fraction CSP3
0.35
Chiral centers
0.0
Largest ring
6.0
QED
0.22
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
FGFR inhibitor
FGFR
Pathway
Protein Tyrosine Kinase/RTK
Source data
