General
Preferred name
TACALCITOL
Synonyms
Curatoderm monohydrate ()
TV 02 monohydrate ()
TV-02H monohydrate ()
1,24(R)-Dihydroxyvitamin D3 monohydrate ()
1,24(R)-Dihydroxyvitamin D3 ()
1.alpha.,24R-Dihydroxyvitamin D3 ()
Tacalcitol monohydrate ()
1,24-dihydroxy Vitamin D3 (hydrate) ()
Bonalfa ()
1.alpha.,24-dihydroxyvitamin d3 ()
Curatoderm ()
P&D ID
PD016354
CAS
57333-96-7
93129-94-3
Tags
available
drug
Drug Status
approved
investigational
experimental
Max Phase
3.0
Drug indication
psoriasis
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
513
DESCRIPTION
Tacalcitol monohydrate(Curatoderm monohydrate), a vitamin D3 analog that promotes bone development by regulating calcium ions, can be used to study psoriasis.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
2
Organisms
0
Compound Sets
11
Axon Medchem Screening Library
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
36
Molecular Weight
416.33
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
6
Ring Count
3
Aromatic Ring Count
0
cLogP
5.56
TPSA
60.69
Fraction CSP3
0.78
Chiral centers
7.0
Largest ring
6.0
QED
0.53
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Calpain
VDR
VDR agonist
Interleukin Related
VD/VDR
Indication
psoriasis, chapped lips
MOA
vitamin D receptor agonist
Pathway
Immunology/Inflammation
Vitamin D Related/Nuclear Receptor
Proteases/Proteasome
Source data
