General
Preferred name
DENUFOSOL
Synonyms
INS-37217 ()
DENUFOSOL TETRASODIUM ()
Denufosol tetrasodium salt ()
INS37217 ()
P&D ID
PD016344
CAS
211448-85-0
318250-11-2
Tags
drug candidate
natural product
Drug indication
Cystic fibrosis
Drug Status
investigational
Max Phase
Phase 3
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
An inhaled drug for the treatment of cystic fibrosis.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
10
BOC Sciences Bioactive Compounds
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugBank
DrugMAP
Guide to Pharmacology
Novartis Chemogenetic Library (NIBR MoA Box)
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
26
Molecular Weight
773.01
Hydrogen Bond Acceptors
21
Hydrogen Bond Donors
9
Rotatable Bonds
14
Ring Count
4
Aromatic Ring Count
2
cLogP
-2.87
TPSA
390.27
Fraction CSP3
0.56
Chiral centers
11.0
Largest ring
6.0
QED
0.09
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Member status
virtual
MOA
Mucin Production, Enhancers
P2Y2 Agonists
Source data
