General
Preferred name
MARAVIROC
Synonyms
UK-427857 ()
Maraviroc-d6 ()
P&D ID
PD016315
CAS
376348-65-1
Tags
available
drug
Drug Status
approved
investigational
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Maraviroc (UK-427857) is a selective CCR5 antagonist with activity against human HIV.
Compound Sets
9
Cayman Chemical Bioactives
14641
28767
CeMM library of unique drugs (CLOUD)
Drug Repurposing Hub
DrugBank
DB04835
DrugBank Approved Drugs
DB04835
EU-OPENSCREEN Bioactive Compound Library
EOS101814
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL1201187
MedChem Express Bioactive Compound Library
HY-13004
NCATS Inxight Approved Drugs
MD6P741W8A
External IDs
27
Properties
(calculated by RDKit )
Molecular Weight
513.33
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
1
Rotatable Bonds
8
Ring Count
5
Aromatic Ring Count
2
cLogP
5.95
TPSA
63.05
Fraction CSP3
0.69
Chiral centers
4.0
Largest ring
6.0
QED
0.47
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
chemokine receptor antagonist
CCR antagonist
CC chemokine receptor antagonist
Target
C-C chemokine receptor type 5
MIP-1¦Á
MIP-1¦Â
CCR5
CCR
HIV
Indication
human immunodeficiency virus (HIV-1)
Pathway
Anti-infection
GPCR/G protein
Immunology/Inflammation
Source data