General
Preferred name
DEOXYCYTIDINE
Synonyms
Cytosine deoxyriboside ()
Deoxyribose cytidine ()
Cytosine deoxyribonucleoside ()
2(1H)-Pyrimidinone ()
Torcitabine ()
2'-Deoxycytidine monohydrate ()
2'-Deoxycytidine (hydrochloride) ()
2'-Deoxycytidine ()
DOXECITINE ()
Doxecitine component of mt-1621 2'-deoxycytidine ()
MT1621 (dC) ()
2'-Deoxycytidine ()
2'-Deoxycytidine hydrochloride ()
P&D ID
PD016190
CAS
25203-63-8
3992-42-5
207121-53-7
56905-41-0
951-77-9
Tags
available
drug
Drug indication
Acute myeloid leukaemia
Myelodysplastic syndrome
Drug Status
approved
experimental
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
2'-Deoxycytidine hydrochloride is the hydrochloride form of 2'-Deoxycytidine, an important deoxyribonucleoside analog commonly used in DNA synthesis and potentially anticancer, and its derivative Gemcitabine has been developed as an anticancer drug.2'-Deoxycytidine 2'-Deoxycytidine hydrochloride protects mice from the lethal toxicity of cytosine arabinoside(araC).
PRICE
29
DESCRIPTION
2'-Deoxycytidine is a deoxyribonucleoside composed of a deoxyribose sugar and a cytosine base. Deoxycytidine is phosphorylated by deoxycytidine kinase.
(Enamine Bioactive Compounds)
DESCRIPTION
2'-Deoxycytidine is one of the major nucleosides of DNA consisting of cytosine and deoxyribose and inhibits the biological effects of bromodeoxyuridine (Brdu). The nucleoside consists only of a pentose sugar attached to a purine or pyrimidine base and has no phosphate group. When N1 is attached to C1 of deoxyribose, deoxyribosides and nucleotides are formed from cytosine and deoxyribose; deoxycytidine monophosphate (dCMP), deoxycytidine diphosphate (dCDP), and deoxycytidine triphosphate (dCTP). cTP is the source of cytosine in RNA (ribonucleic acid) and deoxycytidine triphosphate (dCTP) is the source of deoxycytidine in DNA (deoxyribonucleic acid). Itaconic acid is a polymer.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
12
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DrugMAP
DrugMAP Approved Drugs
Enamine Bioactive Compounds
JUMP-Target 1 Compound Set
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
69
Molecular Weight
227.09
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
3
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
1
cLogP
-1.53
TPSA
110.6
Fraction CSP3
0.56
Chiral centers
3.0
Largest ring
6.0
QED
0.56
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
DCK, TK2
DCK
MOA
DNA polymerase inhibitor
Pathway
Metabolism
Source data
