General
Preferred name
ISAVUCONAZONIUM
Synonyms
ISAVUCONAZONIUM SULFATE ()
Isavuconazonium (sulfate) ()
ISAVUCONAZONIUM CHLORIDE ()
BAL8557-002 ()
BAL8557 ()
Isavuconazonium ion ()
Bal-8557 ()
Isavuconazonium cation ()
BAL-8557000 ()
BAL8557-000 ()
BAL-8557-000 ()
AK-1820 ()
Cresemba ()
AK1820 ()
BAL-8557-002 ()
P&D ID
PD016177
CAS
946075-13-4
742049-41-8
Tags
available
prodrug
drug
Approved by
PMDA
EMA
FDA
First approval
2015
Drug Status
investigational
approved
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
10
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
MedChem Express Bioactive Compound Library
Pandemic Response Box
ReFrame library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
37
Properties
(calculated by RDKit )
Molecular Weight
717.24
Hydrogen Bond Acceptors
12
Hydrogen Bond Donors
2
Rotatable Bonds
13
Ring Count
5
Aromatic Ring Count
5
cLogP
4.58
TPSA
159.37
Fraction CSP3
0.29
Chiral centers
3.0
Largest ring
6.0
QED
0.13
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Microbiology/virology
Anti-infection
Target
Antifungal
inhibits the synthesis of ergosterol
lanosterol 15 alpha-demethylase inhibitor
Fungal
Source data
