General
Preferred name
ML192
Synonyms
ML-192 ()
CID1434953 ()
CID 1434953 ()
ML 192 ()
CID-1434953 ()
ML-192 ()
P&D ID
PD015950
CAS
460331-61-7
Tags
available
probe
Probe info
Probe type
experimental probe
Probe selectivity
protein-selective
Probe sources
Probe targets
[[ compound.targets[t].gene_name ]]
Probe control
Probe control not defined
Orthogonal probes
5
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
ML192 is a selective ligand antagonist of GPR55. ML192 inhibits the ¦Â-arrestin trafficking, ERK1/2 phosphorylation and PKC¦ÂII translocation[1].
PRICE
91
DESCRIPTION
ML192 (CID1434953) is a selective GPR55 ligand antagonist. ML192 is an inhibitor that inhibits ??-arrestin transport, ERK1/2 phosphorylation, and PKC??II translocation.
DESCRIPTION
ML192 (CID1434953) is a selective GPR55 ligand antagonist. ML192 is an inhibitor that inhibits β-arrestin transport, ERK1/2 phosphorylation, and PKCβII translocation.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
5
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
12
Molecular Weight
382.15
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
0
Rotatable Bonds
2
Ring Count
5
Aromatic Ring Count
3
cLogP
3.43
TPSA
62.47
Fraction CSP3
0.45
Chiral centers
0.0
Largest ring
6.0
QED
0.68
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Classification
Probe
Target
Arrestin
ERK
GPR55
PKC
GPR55 Antagonist
GPR
Antitarget
GPR35, CB1, CB2 agonist and antagonist
Pathway
Epigenetics
GPCR/G protein
MAPK/ERK Pathway
Neuronal Signaling
Stem Cell/Wnt
TGF-beta/Smad
Endocrinology/Hormones
Source data
