General
Preferred name
p38 MAPK Inhibitor
Synonyms
p38 MAPK-IN-4 ()
p38 MAP kinase inhibitor ()
P&D ID
PD015724
CAS
219138-24-6
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION p38 MAPK-IN-4 (compound 6) is a p38 MAPK inhibitor with an 50 of 35 nM[1].
PRICE 389
DESCRIPTION Please note that ChEMBL represents this compound as a tautomer of our structure. (GtoPdb)
DESCRIPTION p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase with IC50 value of 35 nM. (BOC Sciences Bioactive Compounds)
DESCRIPTION p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase (IC50 = 35 nM). It inhibits senescence induced by the oncogene RAS. (TargetMol Bioactive Compound Library)
Compound Sets
5
BOC Sciences Bioactive Compounds
p38-map-kinase-inhibitor-cas-219138-24-6-item-162720
Cayman Chemical Bioactives
17650
Guide to Pharmacology
6013
MedChem Express Bioactive Compound Library
HY-112466
TargetMol Bioactive Compound Library
T36010
External IDs
16
Properties
(calculated by RDKit )
Molecular Weight
365.07
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
4
cLogP
4.69
TPSA
50.68
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.57
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
p38 MAPK
Pathway
MAPK/ERK Pathway
MAPK
Source data