General
Preferred name
CASTANOSPERMINE
Synonyms
NSC-625381 ()
P&D ID
PD015692
CAS
79831-76-8
107244-34-8
Tags
drug candidate
natural product
available
Drug indication
Diabetic complication
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Glucosidases alpha and beta inhibitor
(Tocriscreen Plus)
DESCRIPTION
Non-selective MAO inhibitor
(Tocris Bioactive Compound Library)
DESCRIPTION
Glucosidases α and β inhibitor
(Tocriscreen Total)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
2
Compound Sets
13
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugMAP
JUMP-Target 1 Compound Set
Mcule NIBR MoA Box Subset
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
Tocris Bioactive Compound Library
Tocriscreen Plus
Tocriscreen Total
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
29
Molecular Weight
189.1
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
4
Rotatable Bonds
0
Ring Count
2
Aromatic Ring Count
0
cLogP
-2.48
TPSA
84.16
Fraction CSP3
1.0
Chiral centers
5.0
Largest ring
6.0
QED
0.34
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
Enzymes
Primary Target
Glycosylases
MOA
Inhibitor
alpha glucosidase inhibitor
glucosidase inhibitor
Member status
member
Target
GAA, GBA
GAA
Glucosidase
Pathway
Metabolic Enzyme/Protease
Source data
