General
Preferred name
AGN 193109
Synonyms
AGN193109 ()
ICX5609027 ()
AGN 193109-d7 ()
AGN 193109 (sodium salt) ()
P&D ID
PD015537
CAS
171746-21-7
1216429-25-2
2319838-82-7
Tags
available
drug candidate
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Potent and selective RXR agonist
(Tocris Bioactive Compound Library)
DESCRIPTION
AGN 193109 has been found to be a pan-retinoic acid receptor (RAR) antagonist.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
10
BOC Sciences Bioactive Compounds
DrugMAP
DrugMatrix
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NURSA ligand set
TargetMol Bioactive Compound Library
Tocris Bioactive Compound Library
ZINC Tool Compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
26
Molecular Weight
392.18
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
3
cLogP
6.21
TPSA
37.3
Fraction CSP3
0.18
Chiral centers
0.0
Largest ring
6.0
QED
0.53
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolism
Autophagy
Metabolic Enzyme/Protease
Vitamin D Related/Nuclear Receptor
Target
RAR??
RAR/RXR
Primary Target
Retinoic Acid Receptors
MOA
Antagonist
Source data
