General
Preferred name
ECDYSONE
Synonyms
α-Ecdysone ()
.alpha.-Ecdysone ()
¦Á-Ecdysone ()
P&D ID
PD015527
CAS
3604-87-3
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Ecdysone (¦Á-Ecdysone), a major steroid hormone in insects and herbs, triggers mineralocorticoid receptor (MR) activation and induces cellular apoptosis. Ecdysone plays essential roles in coordinating developmental transitions and homeostatic sleep regulation through its active metabolite 20-hydroxyecdysone (Crustecdysone; 20E; HY-N6979)[1][2].
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
4
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
MedChem Express Bioactive Compound Library
NURSA ligand set
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
28
Molecular Weight
464.31
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
5
Rotatable Bonds
5
Ring Count
4
Aromatic Ring Count
0
cLogP
2.74
TPSA
118.22
Fraction CSP3
0.89
Chiral centers
10.0
Largest ring
6.0
QED
0.43
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Apoptosis
Endogenous Metabolite
Pathway
Metabolic Enzyme/Protease
Source data
