General
Preferred name
GBR 12909 dihydrochloride
Synonyms
GBR-12909 dihydrochloride ()
I893 dihydrochloride ()
GBR-12909 ()
Vanoxerine dihydrochloride ()
Vanoxerine 2HCl (GBR-12909) ()
GBR 12909 (hydrochloride) ()
P&D ID
PD015369
CAS
67469-78-7
Tags
natural product
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Selective dopamine reuptake inhibitor
(LOPAC library)
DESCRIPTION
Selective DA uptake inhibitor. Also sigma ligand
(Tocriscreen Plus)
DESCRIPTION
Adenosine uptake inhibitor
(Tocris Bioactive Compound Library)
DESCRIPTION
Selective DA uptake inhibitor. Also σ ligand
(Tocriscreen Total)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
11
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
EU-OPENSCREEN Bioactive Compound Library
Ki Database
LOPAC library
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
Tocris Bioactive Compound Library
Tocriscreen Plus
Tocriscreen Total
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
17
Molecular Weight
522.2
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
10
Ring Count
4
Aromatic Ring Count
3
cLogP
6.16
TPSA
15.71
Fraction CSP3
0.36
Chiral centers
0.0
Largest ring
6.0
QED
0.32
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
Transporters
Selectivity
Reuptake
Pathway
Neuroscience
GPCR/G protein
Target
dopamine uptake
Dopamine Receptor
Primary Target
Dopamine Transporters
MOA
Inhibitor
Source data
