General
Preferred name
BENZAMIDINE HYDROCHLORIDE
Synonyms
Benzamidine HCl ()
Benzamidine (hydrochloride) ()
Benzamidine (hydrochloride) ()
P&D ID
PD015357
CAS
1670-14-0
143504-23-8
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Benzamidine hydrochloride is a trypsin-like serine proteases with Kis of 20, 21, 97, 110, 320 and 750 ¦ÌM against Tryptase, Trypsin, uPA, Factor Xa, Thrombin and tPA, respectively[1].
PRICE
29
DESCRIPTION
Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Ki of 35, 350, and 220 ??M, respectively).
DESCRIPTION
Peptidase inhibitor
(LOPAC library)
DESCRIPTION
Benzamidine is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Kis = 35, 350, and 220 µM, respectively). Benzamidine inhibits the autoactivation of human blood coagulation factor VII, useful as a tool for studying the interactions between this and other relevant growth factors.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Ki of 35, 350, and 220 μM, respectively).
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
6
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
LOPAC library
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
22
Molecular Weight
156.05
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
2
Rotatable Bonds
1
Ring Count
1
Aromatic Ring Count
1
cLogP
1.39
TPSA
49.87
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.47
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
Peptidase
Target
Ser/Thr Protease
Serine Protease
Serine/threonin kinase
Pathway
Metabolic Enzyme/Protease
Cell Cycle/Checkpoint
Metabolism
Proteases/Proteasome
Solubility
Soluble in water.
Source data
