General
Preferred name
PD015273
Synonyms
5-Hydroxyindolacetic acid ()
5-hydroxy-1H-indole-3-acetic acid ()
5-Hydroxyindole-3-acetic acid ()
5-hydroxyindoleacetic acid ()
5-hydroxy Indole-3-acetic Acid ()
5-hydroxy Indole-3-acetic Acid-d6 ()
P&D ID
PD015273
CAS
113303-91-6
55362-47-5
66866-39-5
1321-73-9
54-16-0
2748469-82-9
Tags
drug candidate
natural product
available
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
5-hydroxyindoleacetic acid (5-HIAA; a serotonin metabolite produced by platelets and mast cells) is reported to act via GPR35 as a neutrophil chemoattractant that recruits neutrophils to sites of inflammation .
(GtoPdb)
DESCRIPTION
Serotonin metabolite
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
5
DrugMAP
Guide to Pharmacology
LOPAC library
MedChem Express Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
41
Molecular Weight
191.06
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
3
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
2
cLogP
1.5
TPSA
73.32
Fraction CSP3
0.1
Chiral centers
0.0
Largest ring
6.0
QED
0.67
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolic Enzyme/Protease
Target
Endogenous Metabolite
Source data
