General
Preferred name
ibotenic acid
Synonyms
Ibotenate ()
(±)-Ibotenic acid ()
(RS)-Ibotenic acid ()
DL-Ibotenic acid ()
Ibotenic Acid (CRM) ()
P&D ID
PD015265
CAS
2552-55-8
Tags
drug candidate
natural product
available
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION From the mushrooms Amanita muscaria and Amanita pantherina (GtoPdb)
DESCRIPTION Potent NMDA/metabotropic glutamate receptor agonist; excitotoxin; originally isolated from Amanita pantherina and Amanita muscaria (LOPAC library)
DESCRIPTION Non-selective NMDA agonist (Tocriscreen Total)
DESCRIPTION Ibotenic acid is a neuroexcitatory amino acid originally isolated from amanita species. It is used as a non-selective NMDA and metabotropic glutamate receptor agonist. It is a neurotoxin and is often used to induce brain lesions in animals. It has been used to perform surgery in adult male zebra finches to study reversing reinforcement-induced vocal changes. (BOC Sciences Bioactive Compounds)
Cell lines
0
Organisms
1
Compound Sets
10
AdooQ Bioactive Compound Library
A14006
BOC Sciences Bioactive Compounds
ibotenic-acid-cas-2552-55-8-item-60612
Cayman Chemical Bioactives
38029
14584
DrugMAP
DM8RZE0
DrugMatrix
Guide to Pharmacology
1371
Ki Database
Ibotenate
LOPAC library
MedChem Express Bioactive Compound Library
HY-N2311
Tocriscreen Total
External IDs
26
Properties
(calculated by RDKit )
Molecular Weight
158.03
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
3
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
1
cLogP
-0.95
TPSA
109.32
Fraction CSP3
0.2
Chiral centers
1.0
Largest ring
5.0
QED
0.51
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
NMDA
Pathway
Membrane Transporter/Ion Channel
Neuronal Signaling
Target
iGluR
Source data