General
Preferred name
ibotenic acid
Synonyms
Ibotenate ()
(±)-Ibotenic acid ()
(RS)-Ibotenic acid hydrate ()
DL-Ibotenic acid hydrate ()
(+/-)-Ibotenic acid ()
DL-Ibotenic acid ()
(RS)-Ibotenic acid ()
Ibotenic acid hydrate ()
Ibotenic Acid (CRM) ()
P&D ID
PD015265
CAS
2552-55-8
60573-88-8
Tags
available
drug candidate
natural product
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
From the mushrooms Amanita muscaria and Amanita pantherina
(GtoPdb)
DESCRIPTION
Ibotenic acid has agonist activity at both the N-methyl-D-aspartate (NMDA) and trans-ACPD or metabolotropic quisqualate (Qm) receptor sites.
PRICE
57
PRICE
563
DESCRIPTION
Potent NMDA/metabotropic glutamate receptor agonist; excitotoxin; originally isolated from Amanita pantherina and Amanita muscaria
(LOPAC library)
DESCRIPTION
Non-selective NMDA agonist
(Tocriscreen Total)
DESCRIPTION
Ibotenic acid is a neuroexcitatory amino acid originally isolated from amanita species. It is used as a non-selective NMDA and metabotropic glutamate receptor agonist. It is a neurotoxin and is often used to induce brain lesions in animals. It has been used to perform surgery in adult male zebra finches to study reversing reinforcement-induced vocal changes.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Ibotenic acid (RS-42358-197) has agonist activity at both the NMDA and trans-ACPD or metabotropic quisqualate receptors.
(TargetMol Bioactive Compound Library)
DESCRIPTION
Ibotenic acid hydrate ((RS)-Ibotenic acid hydrate) is an excitatory amino acid receptor agonist that primarily exerts its effects by activating glutamate receptors, such as NMDA receptors. Ibotenic acid hydrate can be extracted from the fly agaric mushroom (Amanita muscaria).
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
12
AdooQ Bioactive Compound Library
BOC Sciences Bioactive Compounds
DrugMAP
DrugMatrix
Guide to Pharmacology
Ki Database
LOPAC library
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
Tocriscreen Total
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
35
Molecular Weight
158.03
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
3
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
1
cLogP
-0.95
TPSA
109.32
Fraction CSP3
0.2
Chiral centers
1.0
Largest ring
5.0
QED
0.51
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
NMDA
Target
NMDA Receptor
iGluR
Pathway
Neuroscience
Membrane Transporter/Ion Channel
Neuronal Signaling
Source data
