General
Preferred name
Dilazep dihydrochloride
Synonyms
Dilazep hydrochloride ()
Dilazep (dihydrochloride) ()
1,4-diazepane-1,4-diyldi-3,1-propanediyl bis(3,4,5-trimethoxybenzoate) dihydrochloride ()
Dilazep (hydrochloride) ()
P&D ID
PD015241
CAS
20153-98-4
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Dilazep dihydrochloride is an inhibitor of adenosine uptake. Dilazep dihydrochloride has cerebral and coronary vasodilating action through enhancement of effect of adenosine. Dilazep dihydrochloride also inhibits the ischemic damage, platelet aggregation, and membrane transport of nucleosides[1][2].
PRICE 79
DESCRIPTION Adenosine uptake inhibitor (LOPAC library)
DESCRIPTION The hydrochloride salt form of Dilazep, which has been found to be an angiotensin converting, adenosine reuptake inhibitor and could be used as a cerebral vasodialator. (BOC Sciences Bioactive Compounds)
DESCRIPTION Adenosine uptake inhibitor (Tocriscreen Total)
DESCRIPTION Dilazep dihydrochloride is an adenosine uptake inhibitor. Dilazep dihydrochloride also inhibits the ischemic damage, membrane transport of nucleosides and platelet aggregation. Dilazep dihydrochloride has cerebral and coronary vasodilating action through enhancement of effect of adenosine. (TargetMol Bioactive Compound Library)
DESCRIPTION Potent and selective DA uptake inhibitor (Tocris Bioactive Compound Library)
Compound Sets
9
BOC Sciences Bioactive Compounds
dilazep-dihydrochloride-cas-20153-98-4-item-115103
Cayman Chemical Bioactives
29761
CZ-OPENSCREEN Bioactive Library
LOPAC library
MedChem Express Bioactive Compound Library
HY-100957
Prestwick Chemical Library
TargetMol Bioactive Compound Library
T15130
Tocris Bioactive Compound Library
0481
Tocriscreen Total
External IDs
16
Properties
(calculated by RDKit )
Molecular Weight
676.25
Hydrogen Bond Acceptors
12
Hydrogen Bond Donors
0
Rotatable Bonds
16
Ring Count
3
Aromatic Ring Count
2
cLogP
4.38
TPSA
114.46
Fraction CSP3
0.55
Chiral centers
0.0
Largest ring
7.0
QED
0.19
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
Uptake
Target
Adenosine uptake
Primary Target
Nucleoside Transporters
MOA
Inhibitor
Pathway
Membrane Transporter/Ion Channel
Source data