General
Preferred name
N-(3,3-Diphenylpropyl)glycinamide
Synonyms
N20C hydrochloride ()
2-((3,3-diphenylpropyl)amino)acetamide hydrochloride ()
N 20C hydrochloride ()
P&D ID
PD015195
CAS
76991-05-4
1177583-87-7
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
118
DESCRIPTION
Non-competitive NMDA receptor open-channel blocker
(Tocriscreen Total)
DESCRIPTION
N20C hydrochloride is a NMDA receptor antagonist with IC50 value of 5 μM. It shows neuroprotective activity in vivo.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
N20C hydrochloride (2-((3,3-diphenylpropyl)amino)acetamide hydrochloride) is a non-competitive NMDA receptor open-channel blocker.
(TargetMol Bioactive Compound Library)
DESCRIPTION
NMDA glutamate receptor open channel blocker.
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
8
Axon Medchem Screening Library
BOC Sciences Bioactive Compounds
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
EU-OPENSCREEN Bioactive Compound Library
LOPAC library
TargetMol Bioactive Compound Library
Tocriscreen Total
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
24
Molecular Weight
268.16
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
7
Ring Count
2
Aromatic Ring Count
2
cLogP
2.28
TPSA
55.12
Fraction CSP3
0.24
Chiral centers
0.0
Largest ring
6.0
QED
0.76
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
NMDA
Target
NMDA Receptor
NMDA antagonist
MOA
glutamate receptor antagonist
Pathway
Neuroscience
Source data
