General
Preferred name
AMN 082 dihydrochloride
Synonyms
AMN082 ()
P&D ID
PD015150
CAS
97075-46-2
Tags
available
drug candidate
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Selective allosteric mGluR7 receptor agonist.
(LOPAC library)
DESCRIPTION
The first selective mGlu7 agonist
(Tocriscreen Plus)
DESCRIPTION
Potent and selective mGlu5 negative allosteric modulator (NAM)
(Tocris Bioactive Compound Library)
DESCRIPTION
The first selective mGlu7 agonist
(Tocriscreen Total)
DESCRIPTION
The hydrochloride salt form of AMN 082 has been found to be a mGlu7 agonist.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
8
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
12
Molecular Weight
464.18
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
9
Ring Count
4
Aromatic Ring Count
4
cLogP
6.59
TPSA
24.06
Fraction CSP3
0.14
Chiral centers
0.0
Largest ring
6.0
QED
0.27
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
7-TM Receptors
Selectivity
mGluR7
Primary Target
Glutamate (Metabotropic) Group III Receptors
MOA
Agonist
Pathway
GPCR/G protein
Neuronal Signaling
Target
mGluR
Source data
