General
Preferred name
NAN-190 hydrobromide
Synonyms
NAN-190 ()
NAN-190 (hydrobromide) ()
P&D ID
PD015145
CAS
115338-32-4
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION NAN-190 hydrobromide is a serotonin receptor 5-HT antagonist. NAN-190 is a selective antagonist of 5-HT1A[1][3].
PRICE 44
DESCRIPTION Potent 5-HT1A serotonin receptor antagonist that lacks TFMPP-like stimulus properties (LOPAC library)
DESCRIPTION The hydrobromide salt form of NAN-190 which is an effective antagonist of 5-HT1A serotonin receptor. (BOC Sciences Bioactive Compounds)
DESCRIPTION 5-HT1A antagonist (Tocriscreen Total)
DESCRIPTION NAN-190 hydrobromide is an antagonist of serotonin receptor 5-HT. (TargetMol Bioactive Compound Library)
DESCRIPTION Potent, standard H3 agonist (Tocris Bioactive Compound Library)
Cell lines
0
Organisms
1
Compound Sets
9
BOC Sciences Bioactive Compounds
nan-190-hydrobromide-cas-115338-32-4-item-209204
Cayman Chemical Bioactives
29314
EU-OPENSCREEN Bioactive Compound Library
EOS101700
Ki Database
NAN-190
LOPAC library
MedChem Express Bioactive Compound Library
HY-19818A
TargetMol Bioactive Compound Library
T12172
Tocris Bioactive Compound Library
0553
Tocriscreen Total
External IDs
17
Properties
(calculated by RDKit )
Molecular Weight
473.13
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
0
Rotatable Bonds
7
Ring Count
4
Aromatic Ring Count
2
cLogP
3.47
TPSA
53.09
Fraction CSP3
0.39
Chiral centers
0.0
Largest ring
6.0
QED
0.45
Structural alerts
2
aggregator (Aggregator Advisor)
Aggregators
aggregator (ZINC)
Aggregators
Related compounds
Custom attributes
(extracted from source data)
Selectivity
5-HT1A
Primary Target
5-HT1A Receptors
MOA
Antagonist
Target
5-HT Receptor
Pathway
GPCR/G protein
Neuronal Signaling
Neuroscience
Solubility
10 mM in DMSO
Source data