General
Preferred name
HYPOTAURINE
Synonyms
2-Aminoethanesulfinic acid ()
2-Aminoethylsulfinic acid ()
P&D ID
PD015114
CAS
300-84-5
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
DESCRIPTION Antioxidant that binds hydroxyl radicals; GABA transport inhibitor (LOPAC library)
DESCRIPTION Hypotaurine is an endogenous inhibitory amino acid for glycine receptor (GlyR). It acts as an antioxidant and a protective agent under physiological conditions. (BOC Sciences Bioactive Compounds)
DESCRIPTION Hypotaurine (2-Aminoethanesulfinic acid), functioning as an intermediate in the biosynthesis of taurine from cysteine within astrocytes, acts as an endogenous inhibitory amino acid targeting the glycine receptor. (TargetMol Bioactive Compound Library)
DESCRIPTION Non-selective, endogenous glycine receptor partial agonist (Tocris Bioactive Compound Library)
Compound Sets
6
BOC Sciences Bioactive Compounds
hypotaurine-cas-300-84-5-105266
Cayman Chemical Bioactives
29614
LOPAC library
MedChem Express Bioactive Compound Library
HY-100803
TargetMol Bioactive Compound Library
T5225
Tocris Bioactive Compound Library
0208
External IDs
32
Properties
(calculated by RDKit )
Molecular Weight
109.02
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
0
Aromatic Ring Count
0
cLogP
-0.83
TPSA
63.32
Fraction CSP3
1.0
Chiral centers
1.0
Largest ring
0.0
QED
0.45
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Selectivity
Antioxidant
Target
Endogenous Metabolite
Glycine receptor
Primary Target
Glycine Receptors
MOA
Agonist
Chloride Channel
Pathway
Metabolic Enzyme/Protease
Membrane Transporter/Ion Channel
Metabolism
Source data