General
Preferred name
Metaproterenol Sulfate
Synonyms
Metaproterenol hemisulfate ()
Orciprenaline sulfate ()
Metaproterenol sulfate, orciprenaline sulfate ()
Metaproterenol hemisulfate salt ()
Prometa ()
TH-152 ()
Orciprenaline sulphate ()
Alupent ()
Alupent Obstetric ()
Metaproterenol sulphate ()
Metaproterenol (hemisulfate) ()
P&D ID
PD015062
CAS
5874-97-5
Tags
natural product
drug
available
Drug indication
Asthma
Drug Status
approved
withdrawn
Max Phase
Phase 4
First approval
1973
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION beta2-Adrenoceptor agonist (LOPAC library)
DESCRIPTION Metaproterenol hemisulfate salt is the hemisulfate salt form of Metaproterenol, which is a moderately selective beta-adrenergic agonist. It is used in the treatment of asthma and bronchospasms. It was developed by Boehringer-Ingelheim and has been withdraw from the market. (BOC Sciences Bioactive Compounds)
Compound Sets
11
BOC Sciences Bioactive Compounds
metaproterenol-hemisulfate-salt-cas-5874-97-5-375669
Cayman Chemical Bioactives
23611
ChEMBL Approved Drugs
CHEMBL1568057
ChEMBL Drugs
CHEMBL1568057
DrugMAP
DMTQS9A
DrugMAP Approved Drugs
DMTQS9A
Enamine BioReference Compounds
LOPAC library
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
metaproterenol-sulfate
TargetMol Bioactive Compound Library
T0277
External IDs
15
Properties
(calculated by RDKit )
Molecular Weight
520.21
Hydrogen Bond Acceptors
10
Hydrogen Bond Donors
10
Rotatable Bonds
8
Ring Count
2
Aromatic Ring Count
2
cLogP
1.61
TPSA
220.04
Fraction CSP3
0.45
Chiral centers
2.0
Largest ring
6.0
QED
0.22
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
beta2
Pathway
GPCR/G protein
Target
??-adrenergic receptor
Solubility
DMSO (Sparingly), Methanol (Sparingly)
Source data