General
Preferred name
(RS)-MCPG
Synonyms
(±)-alpha-Methyl-4-carboxyphenylglycine ()
(RS)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE ()
(R)-MCPG ()
(S)-MCPG ()
(+-)-MCPG ()
MCPG ()
alpha-MCPG ()
(±)-MCPG ()
(RS)-MCPG disodium salt ()
(¡À)-MCPG ()
alpha-MCPG(¡À)-MCPG ()
P&D ID
PD015055
CAS
146669-29-6
1303994-09-3
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION (RS)-MCPG (alpha-MCPG) is a competitive and selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. (RS)-MCPG blocks theta-burst stimulation (TBS)-induced shifts in both juvenile and neonatal rat hippocampal neurons[1][2].
PRICE 57
DESCRIPTION (RS)-MCPG ((??)-MCPG) is a non-selective group I/II metabotropic glutamate receptor antagonist.
DESCRIPTION Competitive metabotropic glutamate receptor antagonist (LOPAC library)
DESCRIPTION (RS)-MCPG is a non-selective group I/group II metabotropic glutamate receptor antagonist. (BOC Sciences Bioactive Compounds)
DESCRIPTION Non-selective mGlu antagonist; active isomer of (RS)-MCPG (Cat. No. 0336) (Tocris Bioactive Compound Library)
DESCRIPTION (RS)-MCPG ((±)-MCPG) is a non-selective group I/II metabotropic glutamate receptor antagonist. (TargetMol Bioactive Compound Library)
DESCRIPTION Selective non-peptide NTS1 antagonist (Tocris Bioactive Compound Library)
DESCRIPTION (RS)-MCPG disodium salt is a non-selective group I/II metabotropic glutamate receptor antagonist. (BOC Sciences Bioactive Compounds)
Compound Sets
7
BOC Sciences Bioactive Compounds
rs-mcpg-cas-146669-29-6-362619
rs-mcpg-disodium-salt-cas-1303994-09-3-item-169391
DrugMatrix
Ki Database
(+-)-MCPG
MCPG
LOPAC library
MedChem Express Bioactive Compound Library
HY-100371
TargetMol Bioactive Compound Library
T3479
Tocris Bioactive Compound Library
0336
3696
External IDs
25
Properties
(calculated by RDKit )
Molecular Weight
209.07
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
1
cLogP
0.64
TPSA
100.62
Fraction CSP3
0.2
Chiral centers
1.0
Largest ring
6.0
QED
0.68
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
Metabotropic
Target
mGluR
Primary Target
Non-selective Metabotropic Glutamate
MOA
Antagonist
Pathway
Neuroscience
GPCR/G protein
Neuronal Signaling
Source data