General
Preferred name
QUAZINONE
Synonyms
Ro-136438 ()
RO-13-6438 ()
RO 13-6438/006 ()
RO-13-6438/006 ()
RO-136438006 ()
Quazinona ()
P&D ID
PD014903
CAS
70018-51-8
Tags
drug candidate
available
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Phosphodiesterase III (PDE III) inhibitor
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
5
Cayman Chemical Bioactives
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
LOPAC library
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
22
Molecular Weight
235.05
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
0
Ring Count
3
Aromatic Ring Count
1
cLogP
1.85
TPSA
44.7
Fraction CSP3
0.27
Chiral centers
1.0
Largest ring
6.0
QED
0.75
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
PDE III
Source data
