General
Preferred name
PHENYLBIGUANIDE
Synonyms
1-PHENYLBIGUANIDE HYDROCHLORIDE ()
1-phenylbiguanide ()
PBG ()
N-Phenylbiguanide ()
Phenylbiguanide (hydrochloride) ()
N-Phenylbiguanide (hydrochloride) ()
PBG (hydrochloride) ()
1-Phenylbiguanide (hydrochloride) ()
Phenylbiguanide, PBG, N-Phenylbiguanide ()
PHENYL BIGUANIDE ()
P&D ID
PD014900
CAS
55-57-2
102-02-3
Tags
available
drug candidate
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Phenylbiguanide hydrochloride is a 5-HT3 receptor selective agonist with an EC50 of 3.0¡À0.1 ¦ÌM.
DESCRIPTION Phenylbiguanide is a 5-HT3 receptor selective agonist with an EC50 of 3.0¡À0.1 ¦ÌM.
PRICE 29
DESCRIPTION Phenylbiguanide (N-Phenylbiguanide) is a 5-HT3 receptor selective agonist(EC50 : 3.0??0.1 ??M)
DESCRIPTION 5-HT3 agonist (Tocriscreen Total)
DESCRIPTION 1-Phenylbiguanide hydrochloride is a 5-HT3 receptor agonist. (BOC Sciences Bioactive Compounds)
DESCRIPTION 5-HT3 Serotonin receptor agonist (LOPAC library)
DESCRIPTION Phenylbiguanide (N-Phenylbiguanide) is a 5-HT3 receptor selective agonist(EC50 : 3.0±0.1 μM) (TargetMol Bioactive Compound Library)
Cell lines
0
Organisms
1
Compound Sets
16
BOC Sciences Bioactive Compounds
1-phenylbiguanide-hydrochloride-cas-55-57-2-27220
Concise Guide to Pharmacology 2017/18
2284
Concise Guide to Pharmacology 2019/20
2284
Concise Guide to Pharmacology 2021/22
2284
Concise Guide to Pharmacology 2023/24
2284
Drug Repurposing Hub
DrugMAP
DMA4XGL
DrugMatrix
Enamine BioReference Compounds
Guide to Pharmacology
2284
Ki Database
PHENYLBIGUANIDE
LOPAC library
MedChem Express Bioactive Compound Library
HY-101331A
HY-101331
Selleckchem Bioactive Compound Library
1-phenylbiguanide
TargetMol Bioactive Compound Library
T7135
Tocriscreen Total
External IDs
56
Properties
(calculated by RDKit )
Molecular Weight
177.1
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
5
Rotatable Bonds
1
Ring Count
1
Aromatic Ring Count
1
cLogP
0.52
TPSA
97.78
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.32
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
5-HT3
Target
5-HT Receptor
HTR3A, HTR3B
MOA
serotonin receptor agonist
Pathway
GPCR/G protein
Neuronal Signaling
Neuroscience
Source data