General
Preferred name
PHENYLBIGUANIDE
Synonyms
1-PHENYLBIGUANIDE HYDROCHLORIDE ()
1-phenylbiguanide ()
N-Phenylbiguanide ()
PBG ()
Phenylbiguanide, PBG, N-Phenylbiguanide ()
1-Phenylbiguanide ()
N-Phenylimidodicarbonimidic Diamide ()
PHENYL BIGUANIDE ()
P&D ID
PD014900
CAS
55-57-2
102-02-3
Tags
drug candidate
natural product
available
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
5-HT3 agonist
(Tocriscreen Total)
DESCRIPTION
1-Phenylbiguanide hydrochloride is a 5-HT3 receptor agonist.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
5-HT3 Serotonin receptor agonist
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
16
BOC Sciences Bioactive Compounds
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugMAP
DrugMatrix
Enamine BioReference Compounds
Guide to Pharmacology
Ki Database
LOPAC library
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
Tocriscreen Total
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
47
Molecular Weight
177.1
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
5
Rotatable Bonds
1
Ring Count
1
Aromatic Ring Count
1
cLogP
0.52
TPSA
97.78
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.32
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
5-HT3
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Target
HTR3A, HTR3B
5-HT Receptor
MOA
serotonin receptor agonist
Source data
