General
Preferred name
MINODRONIC ACID
Synonyms
Minodronate ()
YM-529 ()
YM 529 ()
NSC-725590 ()
ONO-5920 ()
P&D ID
PD014807
CAS
127657-42-5
180064-38-4
Tags
available
probe
drug
Approved by
PMDA
First approval
2011
Drug indication
Osteoporosis
Drug Status
investigational
approved
Max Phase
Phase 3
Probe info
Probe selectivity
protein-selective
Probe type
calculated probe
Probe sources
Probe targets
[[ compound.targets[t].gene_name ]]
Probe control
Orthogonal probes
1
No orthogonal probes found
Similar probes
1
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
2
Organisms
0
Compound Sets
14
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NPC Screening Collection
Probe Miner (suitable probes)
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
30
Properties
(calculated by RDKit )
Molecular Weight
322.01
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
5
Rotatable Bonds
4
Ring Count
2
Aromatic Ring Count
2
cLogP
-0.12
TPSA
152.59
Fraction CSP3
0.22
Chiral centers
0.0
Largest ring
6.0
QED
0.49
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
FDPS, GGPS1
P2X Receptor
Indication
osteoporosis
MOA
bone resorption inhibitor
Pathway
Apoptosis
Membrane Transporter/Ion Channel
Source data
