General
Preferred name
COCARBOXYLASE
Synonyms
Thiamine pyrophosphate ()
cocarboxylase hydrochloride ()
Aneurinepyrophosphoric acid ()
THIAMIN DIPHOSPHATE ()
Thiamine pyrophosphate (chloride) ()
Thiamine pyrophosphate hydrochloride ()
Thiamine pyrophosphate chloride ()
Thiamine Pyrophosphate (chloride) ()
Coenzymate ()
Thiamine diphosphate ()
Pyrophosphoric ester of thiamine ()
Cocarboxilasa ()
Cocarboxylase chloride ()
P&D ID
PD014806
CAS
154-87-0
136-08-3
Tags
available
drug candidate
Drug indication
Discovery agent
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Thiamine pyrophosphate (Cocarboxylase) is a vitamin B-1 derivative that acts as a coenzyme of transketolase. Thiamine pyrophosphate is used in studies to assess decarboxylation mechanisms in biological systems.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
11
Cayman Chemical Bioactives
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugMatrix
EU-OPENSCREEN Bioactive Compound Library
MedChem Express Bioactive Compound Library
NPC Screening Collection
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
52
Molecular Weight
425.04
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
4
Rotatable Bonds
8
Ring Count
2
Aromatic Ring Count
2
cLogP
0.84
TPSA
168.97
Fraction CSP3
0.42
Chiral centers
1.0
Largest ring
6.0
QED
0.35
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
Human Endogenous Metabolite
Vitamin
Pathway
Metabolic Enzyme/Protease
Metabolism
Indication
anemia
Source data
