General
Preferred name
CLORPRENALINE
Synonyms
Clorprenaline HCl ()
20025 ()
NSC 334693 ()
CLORPRENALINE HYDROCHLORIDE ()
Clorprenalina ()
Clopinerin ()
Clorprenaline hydrochloride monohydrate ()
Pentadoll ()
Conselt ()
Fusca ()
Kalutein ()
NSC-334693 ()
Broncon ()
Restanolon ()
(±)-Clorprenaline-d7 ()
Clorprenaline (hydrochloride) ()
P&D ID
PD014780
CAS
6933-90-0
3811-25-4
5588-22-7
2748354-86-9
Tags
available
drug
drug candidate
Drug Status
approved
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Clorprenaline hydrochloride is a ¦Â2-adrenergic receptor agonist that is implicated in bronchial expansion. Clorprenaline has the potential for asthma research[1][2].
PRICE 29
DESCRIPTION Clorprenaline is a potent agonist of ¦Â2-adrenergic. Clorprenaline promotes animal muscular mass growth and decreases fat accumulation. Clorprenaline is a potential new lean meat-boosting feed additive[1].
PRICE 39
DESCRIPTION Clorprenaline is a ??-adrenergic receptor agonist that activates adenylate cyclase and PKA and upregulates cAMP, leading to relaxation of bronchial smooth muscle cells, dilation of the airway, and improvement of airflow. Clorprenaline inhibits the release of mediators, such as histamine and leukotrienes, from mast cells, further promoting its anti-inflammatory properties.
DESCRIPTION Clorprenaline hydrochloride is a β2-adrenergic receptor agonist. It is commonly used for the treatment of bronchial asthma, bronchitis and other respiratory diseases in clinical. (BOC Sciences Bioactive Compounds)
DESCRIPTION Clorprenaline hydrochloride (Clorprenaline HCl) is a beta-2 adrenergic agonist with bronchodilator activity. (TargetMol Bioactive Compound Library)
DESCRIPTION Clorprenaline is a beta-adrenergic receptor agonist. (BOC Sciences Bioactive Compounds)
Compound Sets
12
Cayman Chemical Bioactives
DrugCentral
DrugCentral Approved Drugs
DrugMatrix
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
External IDs
49
Properties
(calculated by RDKit )
Molecular Weight
213.09
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
1
Aromatic Ring Count
1
cLogP
2.37
TPSA
32.26
Fraction CSP3
0.45
Chiral centers
1.0
Largest ring
6.0
QED
0.81
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Adrenergic Receptor
β-adrenergic receptor
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Solubility
Soluble in water (50 mg/ml).
Source data