General
Preferred name
mecillinam
Synonyms
AMDINOCILLIN ()
Mecillinamum ()
Hexacillin ()
Coactin ()
Penicillin HX ()
FL 1060 ()
Mecillinam, Coactin, FL 1060 ()
Selecidin ()
Mecilinam ()
Mecillinam ()
RO-10-9070 ()
RO 10-9070 ()
Selexidin ()
FL-1060 ()
P&D ID
PD014713
CAS
32887-01-7
Tags
available
drug
Approved by
FDA
Drug Status
approved
Max Phase
4.0
Drug indication
bacterial disease
First approval
1984
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Mecillinam (Amdinocillin), the ¦Â-lactam antibiotic, has a broad spectrum of activity against gram-negative organisms[1].
PRICE
32
DESCRIPTION
Mecillinam (Hexacillin), an extended-spectrum penicillin antibiotic, is considered to be active against Gram-negative bacteria by binding specifically to penicillin-binding protein 2 (PBP2). It is used primarily to treat urinary tract infections and has also been used in the treatment of paratyphoid fever and typhoid.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
10
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugCentral
DrugCentral Approved Drugs
MedChem Express Bioactive Compound Library
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
28
Molecular Weight
325.15
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
3
Aromatic Ring Count
0
cLogP
1.41
TPSA
73.21
Fraction CSP3
0.8
Chiral centers
3.0
Largest ring
7.0
QED
0.48
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Bacterial
antibiotic
Antibiotics,Bacterial
Indication
urinary tract infections, gram-negative bacterial infections
MOA
bacterial cell wall synthesis inhibitor
Pathway
Microbiology/virology
Anti-infection
Source data
