General
Preferred name
PRAVADOLINE
Synonyms
Pravadoline (WIN 48098) ()
PRAVADOLINE MALEATE ()
WIN-48098-6 ()
WIN 48,098-6 ()
P&D ID
PD014688
CAS
92623-84-2
92623-83-1
Tags
available
drug candidate
Drug indication
Analgesic
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Pravadoline is a COX inhibitor and cannabinoid CB agonist used as an anti-inflammatory and analgesic agent. It inhibits prostaglandin synthesis, and it also suppresses neuronally stimulated contractions in mouse model, which differs from NSAIDs.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
10
AdooQ Bioactive Compound Library
Axon Medchem Screening Library
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugMAP
DrugMatrix
NPC Screening Collection
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
25
Molecular Weight
378.19
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
0
Rotatable Bonds
6
Ring Count
4
Aromatic Ring Count
3
cLogP
3.52
TPSA
43.7
Fraction CSP3
0.35
Chiral centers
0.0
Largest ring
6.0
QED
0.62
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
CNR1, CNR2
COX inhibitor
CB agonist
MOA
cyclooxygenase inhibitor
Source data
