General
Preferred name
XIPAMIDE
Synonyms
Diurexan ()
Aquaphor ()
MJF-10938 ()
MJF 10,938 ()
BE-1293 ()
Xipamida ()
P&D ID
PD014677
CAS
135274-05-4
14293-44-8
Tags
available
drug
Drug Status
approved
experimental
investigational
Max Phase
2.0
Drug indication
Cardiovascular disease
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Xipamide is a sulfonamide-based diuretic. Xipamide is an antihypertensive agent able to selectively inhibit the anion exchanger (AE)[1].
PRICE 35
DESCRIPTION Xipamide is a sulfonamide diuretic. (GtoPdb)
DESCRIPTION Xipamide (Diurexan) is a sulfonamide-based diuretic with antihypertensive properties. Xipamide selectively inhibits anion exchanger. (TargetMol Bioactive Compound Library)
Compound Sets
12
ChEMBL Drugs
CHEMBL517199
Drug Repurposing Hub
DrugBank
DB13803
DrugCentral
2853
DrugCentral Approved Drugs
2853
DrugMatrix
Guide to Pharmacology
7900
MedChem Express Bioactive Compound Library
HY-W042301
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
xipamide
TargetMol Bioactive Compound Library
T17266
External IDs
25
Properties
(calculated by RDKit )
Molecular Weight
354.04
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
3
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
2
cLogP
2.56
TPSA
109.49
Fraction CSP3
0.13
Chiral centers
0.0
Largest ring
6.0
QED
0.79
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Indication
edema, hypertension
Target
SLC12A3
Anion Exchangers
MOA
Carbonic anhydrase inhibitor
Pathway
Membrane Transporter/Ion Channel
Source data