General
Preferred name
AROFYLLINE
Synonyms
LAS 31025 ()
LAS-31025 ()
Arofilina ()
P&D ID
PD014619
CAS
136145-07-8
Tags
drug candidate
available
Drug indication
Chronic obstructive pulmonary disease
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
482
DESCRIPTION
Arofylline (LAS 31025) is a PDE4 inhibitor and can be used for asthma studies.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
7
ChEMBL Drugs
Drug Repurposing Hub
DrugMAP
DrugMatrix
NPC Screening Collection
ReFrame library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
23
Molecular Weight
304.07
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
3
Aromatic Ring Count
3
cLogP
1.94
TPSA
72.68
Fraction CSP3
0.21
Chiral centers
0.0
Largest ring
6.0
QED
0.8
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
PDE4
PDE4A
MOA
phosphodiesterase inhibitor
Pathway
Metabolism
Source data
