General
Preferred name
DESLORELIN
Synonyms
Deslorelin acetate ()
H 4065 ()
Somagard ()
Deslorelin acetate(57773-65-6 free base) ()
Deslorelina ()
Desloreline ()
D-TRP-LHRH-PEA ()
D-TRP LHRH-PEA ()
Suprelorin ()
Deslorelin (acetate) ()
P&D ID
PD014602
CAS
82318-06-7
57773-65-6
1642579-30-3
Tags
available
drug
drug candidate
Approved by
FDA
Drug Status
vet_approved
approved
investigational
Max Phase
2.0
Drug indication
Hereditary breast and ovarian cancer syndrome
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION GnRH peptide agonist (GtoPdb)
DESCRIPTION Deslorelin acetate(57773-65-6 free base) is a gonadotropin releasing hormone super-agonist (GnRH agonist) (TargetMol Bioactive Compound Library)
Compound Sets
11
Cayman Chemical Bioactives
34041
ChEMBL Drugs
CHEMBL2365665
CHEMBL2357192
Drug Repurposing Hub
DrugBank
DB11510
DrugBank Approved Drugs
DB11510
DrugCentral
5673
Guide to Pharmacology
9343
Natural product-based probes and drugs
NPC Screening Collection
ReFrame library
TargetMol Bioactive Compound Library
TP2323L
External IDs
48
Properties
(calculated by RDKit )
Molecular Weight
1281.64
Hydrogen Bond Acceptors
14
Hydrogen Bond Donors
17
Rotatable Bonds
32
Ring Count
8
Aromatic Ring Count
6
cLogP
-0.55
TPSA
444.83
Fraction CSP3
0.44
Chiral centers
9.0
Largest ring
6.0
QED
0.01
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
GNRHR
Pathway
GPCR/G protein
MOA
gonadotropin releasing factor hormone receptor agonist
Biosynthetic Origin
Peptide (Ribosomal)
Therapeutic Indication
Hormone
Therapeutic Class
Hormone Therapy
Source data